ACS Nano

KEYWORDS:SmartMaterials,Microspheres,Preparation,Microstructure,PhysicalStimulus,ChemicalStimulus,BiologicalStimulus,  Stimuli-ResponsiveProperties,Applications

 Smart polymer microspheres (SPMs) are a class  of stimulus-responsive materials that undergo physical,  chemical,or property changes in response to external stimuli,  such as temperature, pH, light, and magnetic fields. In recent years, their diver seresponsivenessandtunable structures have  enabled broad applications in biomedicine, environmental protection, information encryption, and other fields. This  studyprovidesadetailedreviewofrecentpreparationmethods  ofSPMs, focusingonphysicalmethodssuchasemulsification solventevaporation,microfluidics,andelectrostaticsprayingas  wellaschemicalapproachessuchasemulsionandprecipitation  polymerization.Meanwhile,different typesof stimulus-respon sivebehaviors,suchastemperature-,pH-, light-,andmagnetic responsiveness, are thoroughly examined. This study also explores the applications of SPMs in drug delivery, tissue  engineering,andenvironmentalmonitoring,whilediscussingfuturetechnologicalchallengesanddevelopmentdirections in  thisfield.

TaoGuo, LanLuo, LinlinWang, FenghuaZhang, YanjuLiu, JinsongLeng

Smart Polymer Microspheres-Preparation-Microstructures,-Stimuli-Responsive Properties- and Applications.pdf